Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells

  title={Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells},
  author={Paul D. R. Gamlin and David Harry McDougal and Joel Pokorny and Vivianne C. Smith and K. K. C. Yau and Dennis M. Dacey},
  journal={Vision Research},
Melanopsin, a novel photopigment, has recently been localized to a population of retinal ganglion cells that display inherent photosensitivity. During continuous light and following light offset, primates are known to exhibit sustained pupilloconstriction responses that resemble closely the photoresponses of intrinsically-photoreceptive ganglion cells. We report that, in the behaving macaque, following pharmacological blockade of conventional photoreceptor signals, significant pupillary… CONTINUE READING
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Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2012
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