Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals.

@article{Riel2007HumanAA,
  title={Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals.},
  author={Debby van Riel and Vincent Munster and Emmie de Wit and G F Rimmelzwaan and Ron A M Fouchier and Albert D M E Osterhaus and Thijs Kuiken},
  journal={The American journal of pathology},
  year={2007},
  volume={171 4},
  pages={1215-23}
}
Viral attachment to the host cell is critical for tissue and species specificity of virus infections. Recently, pattern of viral attachment (PVA) in human respiratory tract was determined for highly pathogenic avian influenza virus of subtype H5N1. However, PVA of human influenza viruses and other avian influenza viruses in either humans or experimental animals is unknown. Therefore, we compared PVA of two human influenza viruses (H1N1 and H3N2) and two low pathogenic avian influenza viruses… CONTINUE READING
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