Human amniotic fluid stem cells: a new perspective

@article{Siegel2007HumanAF,
  title={Human amniotic fluid stem cells: a new perspective},
  author={Nicol Siegel and Margit Rosner and Michaela Hanneder and Angelika Freilinger and Markus Hengstschl{\"a}ger},
  journal={Amino Acids},
  year={2007},
  volume={35},
  pages={291-293}
}
Summary.The discovery of amniotic fluid stem cells initiated a new and very promising field in stem cell research. In the last four years amniotic fluid stem cells have been shown to express markers specific to pluripotent stem cells, such as Oct-4. Due to their high proliferation potential, amniotic fluid stem cell lineages can be established. Meanwhile, they have been shown to harbor the potential to differentiate into cells of all three embryonic germ layers. It will be a major aim for the… 
Human amniotic fluid: a source of stem cells for possible therapeutic use.
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TLDR
The approach to generate clonal amniotic fluid stem cell lines as new tools to investigate molecular and cell biological consequences of human natural occurring disease causing mutations is discussed.
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TLDR
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TLDR
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Induction of mesenchymal/epithelial marker expression in human amniotic fluid stem cells.
Amniotic fluid-derived stem cells for cardiovascular tissue engineering applications.
TLDR
Several tissue engineering and regenerative therapeutic approaches for the use of AFSC in heart patches, injection after myocardial infarction, heart valves, vascularized scaffolds, and blood vessels show great promise in the treatment of congenital cardiovascular defects.
Intercellular protein expression variability as a feature of stem cell pluripotency
TLDR
For a better understanding of stemness it will be indispensable to separately investigate the issue of intercellular variability for each feature of pluripotency.
Intercellular protein expression variability as a feature of stem cell pluripotency
TLDR
For a better under- standing of stemness it will be indispensable to separately investigate the issue of intercellular variability for each feature of pluripotency.
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The authors review the current state of knowledge about amniotic fluid cells to identify potential new sources for the isolation of progenitor cells or stem cells, without raising the ethical issues involved in embryonic stem cell research.
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A reliable quantitative method of estimating the degree of intrauterine asphyxia, other than from changes in the foetal heart-rate, would be useful, so attempts have been made to use its pH, pC0, and PO, as an index of the condition of the foetus.
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