Human amniotic epithelial stem cells promote wound healing by facilitating migration and proliferation of keratinocytes via ERK, JNK and AKT signaling pathways

@article{Zhao2016HumanAE,
  title={Human amniotic epithelial stem cells promote wound healing by facilitating migration and proliferation of keratinocytes via ERK, JNK and AKT signaling pathways},
  author={Bin Zhao and Jia-qi Liu and Zhao Zheng and Jun Zhang and Shu-Yue Wang and Shi-Chao Han and Qin Zhou and Hao Guan and Chao Li and Lin-Lin Su and Dahai Hu},
  journal={Cell and Tissue Research},
  year={2016},
  volume={365},
  pages={85-99}
}
Wound healing is a highly orchestrated physiological process consisting in a complex interaction of cellular and biochemical events. Human amniotic epithelial stem cells (HAESCs) have been shown to be an attractive resource for wound healing because they are primitive stem cells. However, the exact effects of amnion-derived stem cells on the migration or proliferation of keratinocytes and their potential mechanism are not fully understood. We have found that HAESCs accelerate the migration of… CONTINUE READING
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