Human age-related cataract and lens epithelial cell death.

@article{Harocopos1998HumanAC,
  title={Human age-related cataract and lens epithelial cell death.},
  author={George J. Harocopos and K H Masorra Alvares and Allan E. Kolker and David C. Beebe},
  journal={Investigative ophthalmology & visual science},
  year={1998},
  volume={39 13},
  pages={
          2696-706
        }
}
PURPOSE To evaluate the importance of lens epithelial cell death in age-related cataract. To determine whether the large percentage of terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end labeling (TUNEL)-positive lens epithelial cells previously reported in human capsulotomy specimens results from apoptosis or necrosis. METHODS Capsulotomy specimens from patients who had undergone cataract surgery and epithelia from cataractous lenses of eye bank eyes were compared with… CONTINUE READING

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