Human adipose-derived stem cells display myogenic potential and perturbed function in hypoxic conditions.

@article{Lee2006HumanAS,
  title={Human adipose-derived stem cells display myogenic potential and perturbed function in hypoxic conditions.},
  author={Jee Hyung Lee and Daniel M. Kemp},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={341 3},
  pages={882-8}
}
Here, we enriched a human cell population from adipose tissue that exhibited both mesenchymal plasticity, self-renewal capacity, and a cell-surface marker profile indistinguishable from that of bone marrow-derived mesenchymal stem cells. In addition to adipogenic and osteogenic differentiation, these adipose-derived stem cells displayed skeletal myogenic potential when co-cultured with mouse skeletal myocytes in reduced serum conditions. Physical incorporation of stem cells into multinucleated… CONTINUE READING

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