Human adenovirus type 19 infection of corneal cells induces p38 MAPK-dependent interleukin-8 expression

@article{Rajaiya2007HumanAT,
  title={Human adenovirus type 19 infection of corneal cells induces p38 MAPK-dependent interleukin-8 expression},
  author={Jaya Rajaiya and Jingnan Xiao and Raju V. S. Rajala and James Chodosh},
  journal={Virology Journal},
  year={2007},
  volume={5},
  pages={17 - 17}
}
BackgroundHuman adenovirus type 19 (HAdV-19) is a major cause of epidemic keratoconjunctivitis, the only ocular adenoviral infection associated with prolonged corneal inflammation. In this study, we investigated the role of p38 mitogen-activated protein kinase (MAPK) in HAdV-19 infection, with particular attention to the role of p38 MAPK in the transcriptional control of interleukin-8 (IL-8), a chemokine previously shown to be central to the initiation of adenovirus keratitis.ResultsWe found… CONTINUE READING

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