Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.

@article{Song2006HumanAA,
  title={Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.},
  author={Bao-Liang Song and Can-Hua Wang and Xiao-min Yao and Li Yang and Wen-jing Zhang and Zhen-Zhen Wang and X Zhao and Jin-bo Yang and Wei Qi and X Yang and Kenji Inoue and Zhi-xin Lin and Hui-Zhan Zhang and Tatsuhiko Kodama and Catherine C. Y. Chang and Yin-kun Liu and T. Y. P. Chang and Boliang Li},
  journal={The Biochemical journal},
  year={2006},
  volume={394 Pt 3},
  pages={617-26}
}
Humans express two ACAT (acyl-CoA:cholesterol acyltransferase) genes, ACAT1 and ACAT2. ACAT1 is ubiquitously expressed, whereas ACAT2 is primarily expressed in intestinal mucosa and plays an important role in intestinal cholesterol absorption. To investigate the molecular mechanism(s) responsible for the tissue-specific expression of ACAT2, we identified… CONTINUE READING