Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties.

@article{Calleja1994HumanAT,
  title={Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties.},
  author={Maria C Calleja and Guido Persoone and Paul Geladi},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={1994},
  volume={32 2},
  pages={173-87}
}
Five acute bioassays consisting of three cyst-based tests (with Artemia salina, Streptocephalus proboscideus and Brachionus calyciflorus), the Daphnia magna test and the bacterial luminescence inhibition test (Photobacterium phosphoreum) are used to determine the acute toxicity of the 50 priority chemicals of the Multicentre Evaluation of In Vitro Cytotoxicity (MEIC) programme. These tests and five physiocochemical properties (n-octanol-water partition coefficient, molecular weight, melting… CONTINUE READING