Human acid-labile interferon alpha.


In acquired immune deficiency syndrome (AIDS) and autoimmune diseases, like systemic lupus erythematosus (SLE), persisting high levels of interferon (IFN) are detectable in plasma. The IFN has been identified as an unusual human acid-labile IFN-alpha (al-IFN-alpha). Its properties are similar to that of the known alpha interferons except sensitivity to acid… (More)