Human Umbilical Cord Mesenchymal Stem Cell Exosomes Enhance Angiogenesis Through the Wnt4/β‐Catenin Pathway

@article{Zhang2015HumanUC,
  title={Human Umbilical Cord Mesenchymal Stem Cell Exosomes Enhance Angiogenesis Through the Wnt4/β‐Catenin Pathway},
  author={B. Zhang and X. Wu and X. Zhang and Yaoxiang Sun and Yongmin Yan and Hui Shi and Yan-hua Zhu and L. Wu and Z. Pan and W. Zhu and Hui Qian and Wenrong Xu},
  journal={STEM CELLS Translational Medicine},
  year={2015},
  volume={4}
}
Human umbilical cord mesenchymal stem cells (hucMSCs) and their exosomes have been considered as potential therapeutic tools for tissue regeneration; however, the underlying mechanisms are still not well understood. In this study, we isolated and characterized the exosomes from hucMSCs (hucMSC‐Ex) and demonstrated that hucMSC‐Ex promoted the proliferation, migration, and tube formation of endothelial cells in a dose‐dependent manner. Furthermore, we demonstrated that hucMSC‐Ex promoted wound… Expand
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References

SHOWING 1-10 OF 61 REFERENCES
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis.
  • 474
Lentivirus‐modified human umbilical cord mesenchymal stem cells maintain their pluripotency
  • 18
Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis
  • 148
  • PDF
...
1
2
3
4
5
...