Human Tear Serotonin Levels Correlate with Symptoms and Signs of Dry Eye.

@article{Chhadva2015HumanTS,
  title={Human Tear Serotonin Levels Correlate with Symptoms and Signs of Dry Eye.},
  author={Priyanka Chhadva and Tinthu Lee and Constantine D. Sarantopoulos and Abigail S. Hackam and Allison L. McClellan and Elizabeth Roy Felix and Roy C Levitt and Anat Galor},
  journal={Ophthalmology},
  year={2015},
  volume={122 8},
  pages={1675-80}
}
PURPOSE Serotonin, a neurotransmitter known to be involved in nociceptor sensitization, is present in human tears. The purpose of this study was to correlate tear serotonin levels, as a marker of nociceptor sensitization, to facets of dry eye (DE), including symptoms and signs. DESIGN Cross-sectional study. PARTICIPANTS A total of 62 patients with normal eyelid and corneal anatomy were prospectively recruited from a Veterans Administration Ophthalmology Clinic over 11 months. METHODS Dry… CONTINUE READING
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