Human T lymphotropic virus type I (HTLV-I) proviral load in cerebrospinal fluid: a new criterion for the diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis?

@article{Lzin2005HumanTL,
  title={Human T lymphotropic virus type I (HTLV-I) proviral load in cerebrospinal fluid: a new criterion for the diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis?},
  author={Agn{\`e}s L{\'e}zin and Stephane Olindo and St{\'e}phanie Oli{\`e}re and Michel Varrin-Doyer and R{\'e}gine Marlin and Philippe Cabre and Didier Smadja and Raymond C{\'e}saire},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={191 11},
  pages={1830-4}
}
Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is associated with accumulation of HTLV-I-infected T cells in the central nervous system (CNS). However, data on HTLV-I proviral load in the CNS at the asymptomatic stage are still lacking. We measured HTLV-I proviral load in cerebrospinal fluid (CSF) cells from 17 patients with HAM/TSP and 25 asymptomatic carriers. The percentage of HTLV-I-infected cells in CSF cells and the CSF cell… CONTINUE READING
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