Human T-cell leukemia virus type I trans activator induces class I major histocompatibility complex antigen expression in glial cells.

Transfection of the tax gene encoding the trans activator of human T-cell leukemia virus type I into glial line cells induced class I major histocompatibility complex (MHC) antigens on these cells. This occurred through the interaction of tax protein with the gene encoding class I MHC antigens but not through any soluble factors, such as interferons, or… CONTINUE READING