Human T cell leukemia virus type-I Tax activates human macrophage inflammatory protein-3 α / CCL 20 gene transcription via the NF-κ B pathway

@inproceedings{Imaizumi2002HumanTC,
  title={Human T cell leukemia virus type-I Tax activates human macrophage inflammatory protein-3 α / CCL 20 gene transcription via the NF-κ B pathway},
  author={Yoshitaka Imaizumi and Shinichi Sugita and Kazuo Yamamoto and Daisuke Imanishi and Tomoko Kohno and Masao Tomonaga and Toshifumi Matsuyama},
  year={2002}
}
Infection by human T cell leukemia virus type (HTLV)-I is associated with several diseases, including adult T cell leukemia and HTLV-I-associated myelopathy/tropical spastic paraparesis. Leukocytes are attracted to the sites of inflammation by chemotactic factors. Macrophage inflammatory protein (MIP)-3α/CCL20 is a recently isolated member of the CC subfamily of chemokines and has been proposed as a crucial factor to elicit inflammatory reactions. We now report that endogenous MIP-3α mRNA… CONTINUE READING

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