Human T cell epitope mapping of the Schistosoma mansoni 14-kDa fatty acid-binding protein using cells from patients living in areas endemic for schistosomiasis.

@article{Fonseca2005HumanTC,
  title={Human T cell epitope mapping of the Schistosoma mansoni 14-kDa fatty acid-binding protein using cells from patients living in areas endemic for schistosomiasis.},
  author={Cristina T Fonseca and Edecio Cunha-Neto and Anna Carla Goldberg and Jorge Agle Kalil and Am{\'e}lia Maria Ribeiro de Jesus and Edgard M Carvalho and Rodrigo Corr{\^e}a-Oliveira and Sergio Costa Oliveira},
  journal={Microbes and infection},
  year={2005},
  volume={7 2},
  pages={204-12}
}
The development of a defined anti-schistosomiasis vaccine would contribute to the current control strategy mainly because immunization provides long-lasting immunity to the disease. Sm14, one of the six Schistosoma mansoni antigens selected by WHO as a candidate to compose a subunit vaccine against schistosomiasis, has been associated with resistance to S. mansoni infection in human beings and is able to induce protection in the murine model. To identify human T cell epitopes in Sm14, we used… CONTINUE READING