Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset.

@article{Galy1995HumanTB,
  title={Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset.},
  author={Anne Galy and Marilyn Travis and Dazhi Cen and Bilei Chen},
  journal={Immunity},
  year={1995},
  volume={3 4},
  pages={459-73}
}
The early stages of lymphoid cell formation were studied by testing the differentiative potential of phenotypically defined subsets of CD34+ bone marrow cells. A subpopulation of CD34+ Lin- CD45RA+ cells expressing CD10 was isolated by flow cytometry. Such cells are CD38+, HLA-DR+, do not express significant levels of Thy-1 and c-kit, lack erythroid, myeloid, megakaryocytic potential, and give rise only to lymphoid T, B, natural killer (NK), and dendritic cells (DC) in kinetics and titration… CONTINUE READING
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