Human Stiff-Person Syndrome IgG Induces Anxious Behavior in Rats

Abstract

BACKGROUND Anxiety is a heterogeneous behavioral domain playing a role in a variety of neuropsychiatric diseases. While anxiety is the cardinal symptom in disorders such as panic disorder, co-morbid anxious behavior can occur in a variety of diseases. Stiff person syndrome (SPS) is a CNS disorder characterized by increased muscle tone and prominent… (More)
DOI: 10.1371/journal.pone.0016775

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