Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

@inproceedings{Iovino2010HumanSC,
  title={Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction},
  author={Mariangela Iovino and Rickie Patani and Colin Watts and Siddharthan Chandran and Maria Grazia Spillantini},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Intracellular filamentous deposits containing microtubule-associated protein tau constitute a defining characteristic of many neurodegenerative disorders. Current experimental models to study tau pathology in vitro do not usually recapitulate the tau expression pattern characteristic of adult human brain. In this study, we have investigated… CONTINUE READING