Human Schwann cells in vitro. I. Failure to differentiate and support neuronal health under co-culture conditions that promote full function of rodent cells.

@article{Morrissey1995HumanSC,
  title={Human Schwann cells in vitro. I. Failure to differentiate and support neuronal health under co-culture conditions that promote full function of rodent cells.},
  author={Tom Morrissey and Richard P. Bunge and Naomi Kleitman},
  journal={Journal of neurobiology},
  year={1995},
  volume={28 2},
  pages={171-89}
}
Schwann cells (SCs) play critical roles in regeneration after injury to the peripheral nervous system and can also induce axonal regeneration in the central nervous system. Transplantation of purified SCs into sites of neural injury in rodents has confirmed the remarkable ability of these cells to promote axonal regrowth, suggesting that human application of SC transplantation could be valuable. In this report, we have compared the functional capacities of SCs derived from adult human and… CONTINUE READING
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