Human RGM249-derived small RNAs potentially regulate tumor malignancy.

Abstract

The human noncoding RNA gene RGM249 has been shown to regulate the degree of cancer cell differentiation. In this study, we investigated the effects of 3 microRNA-like molecules digested from RGM249 on the loss of malignant properties in cancer cells in immunodeficient KSN/Slc mice. We utilized small interfering RNAs (siRNAs) alone or in combination with a… (More)
DOI: 10.1089/nat.2013.0424

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