Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12.

@article{Miyashita1995HumanRF,
  title={Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12.},
  author={Hideyuki Miyashita and Kan-ichi Nakagawara and Mitsuko Mori and Yoichi Narushima and Naoya Noguchi and S Moriizumi and Shin Takasawa and Hideto Yonekura and Takashi Takeuchi and Hitoshi Okamoto},
  journal={FEBS letters},
  year={1995},
  volume={377 3},
  pages={429-33}
}
Reg, first isolated from a rat regenerating islet cDNA library, is expressed in regenerating islet beta-cells. Recently, it has been revealed that Reg and Reg-related genes constitute a multigene family, the Reg family. In human, the four REG family genes, i.e., REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP, have so far been isolated. In this study, we analyzed YAC clones containing the four genes and performed two-color FISH to determine the map order of the genes. The human… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Regenerating gene (REG) product and its potential clinical usage.

Expert opinion on therapeutic targets • 2016
View 1 Excerpt

Helicobacter and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements.

American journal of physiology. Gastrointestinal and liver physiology • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…