Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics

  title={Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics},
  author={J. Riba and Marta Valle and G. Urbano and M. Yritia and A. Morte and M. Barbanoj},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  pages={73 - 83}
  • J. Riba, Marta Valle, +3 authors M. Barbanoj
  • Published 2003
  • Medicine
  • Journal of Pharmacology and Experimental Therapeutics
  • The effects of the South American psychotropic beverage ayahuasca on subjective and cardiovascular variables and urine monoamine metabolite excretion were evaluated, together with the drug's pharmacokinetic profile, in a double-blind placebo-controlled clinical trial. [...] Key Method Eighteen volunteers with prior experience in the use of psychedelics received single oral doses of encapsulated freeze-dried ayahuasca (0.6 and 0.85 mg of DMT/kg of body weight) and placebo. Ayahuasca produced significant…Expand Abstract
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