Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics
@article{Riba2003HumanPO, title={Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics}, author={Jordi Riba and Marta Valle and Gloria Urbano and Mercedes Yritia and Adelaida Morte and Manel J. Barbanoj}, journal={Journal of Pharmacology and Experimental Therapeutics}, year={2003}, volume={306}, pages={73 - 83} }
The effects of the South American psychotropic beverage ayahuasca on subjective and cardiovascular variables and urine monoamine metabolite excretion were evaluated, together with the drug's pharmacokinetic profile, in a double-blind placebo-controlled clinical trial. [] Key Method Eighteen volunteers with prior experience in the use of psychedelics received single oral doses of encapsulated freeze-dried ayahuasca (0.6 and 0.85 mg of DMT/kg of body weight) and placebo. Ayahuasca produced significant…
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