Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review

  title={Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review},
  author={Aim{\'e}e R. Kreimer and Gary M. Clifford and Peter Boyle and Silvia Franceschi},
  journal={Cancer Epidemiology Biomarkers \& Prevention},
  pages={467 - 475}
Mucosal human papillomaviruses (HPV) are the cause of cervical cancer and likely a subset of head and neck squamous cell carcinomas (HNSCC), yet the global prevalence and type distribution of HPV in HNSCC remains unclear. We systematically reviewed published studies of HNSCC biopsies that employed PCR-based methods to detect and genotype HPV to describe the prevalence and type distribution of HPV by anatomic cancer site. Geographic location and study size were investigated as possible sources… 

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