Human PEG1/MEST, an imprinted gene on chromosome 7.

  title={Human PEG1/MEST, an imprinted gene on chromosome 7.},
  author={Shin Kobayashi and Takashi Kohda and Naoki Miyoshi and Yoshimi Kuroiwa and Kazuo Aisaka and Osamu Tsutsumi and Tomoko Kaneko-ishino and F. Ishino},
  journal={Human molecular genetics},
  volume={6 5},
The mouse Peg1/Mest gene is an imprinted gene that is expressed particularly in mesodermal tissues in early embryonic stages. It was the most abundant imprinted gene among eight paternally expressed genes (Peg 1-8) isolated by a subtraction-hybridization method from a mouse embryonal cDNA library. It has been mapped to proximal mouse chromosome 6, maternal duplication of which causes early embryonic lethality. The human chromosomal region that shares syntenic homology with this is 7q21-qter… CONTINUE READING
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