Human PAX gene expression and development of the vertebral column.

  title={Human PAX gene expression and development of the vertebral column.},
  author={Craig A Smith and Rocky S Tuan},
  journal={Clinical orthopaedics and related research},
The human gene HuP48 is a member of the PAX family of developmental control genes. Common to all members of this family is a highly conserved DNA sequence, the paired box sequence. In several species, paired box-containing genes function in normal embryonic morphogenesis. To investigate the possible involvement of PAX genes in the development of the human skeleton, the authors analyzed the expression of the paired box-containing gene, HuP48, in the fetal human vertebral column. In addition, the… CONTINUE READING


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