Human Ntera2 cells as a predictive in vitro test system for developmental neurotoxicity

@article{Stern2013HumanNC,
  title={Human Ntera2 cells as a predictive in vitro test system for developmental neurotoxicity},
  author={Michael Stern and Andrea Gierse and Saime Tan and Gerd Bicker},
  journal={Archives of Toxicology},
  year={2013},
  volume={88},
  pages={127-136}
}
Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the “3Rs” (reduction, replacement, and refinement) of animal testing, alternative testing strategies are needed in order to refine and reduce animal experiments and allow faster and less expensive screening. The goal of this study was to establish components for a human cell… CONTINUE READING

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