Human Neutrophil Plasminogen Activator Is Localized in Specific Granules and Is Translocated to the Cell Surface by Exocytosis by Jeanne M , Heiple

Plasminogen activator (PA)' is produced and secreted by mouse and human monocytes and neutrophils (1-4). A role for the enzyme in cell migration associated with inflammation has been postulated (5) . Recently, a specific PA receptor on the surface of monocytes has been described (6, 7) . PA bound to this receptor remains active, providing a mechanism… CONTINUE READING