Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity.

@article{Evjenth2009HumanN,
  title={Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity.},
  author={Rune H Evjenth and Kristine Hole and Odd Andr{\'e} Karlsen and Mathias Ziegler and Thomas Arnesen and Johan Richard Lillehaug},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 45},
  pages={
          31122-9
        }
}
Protein acetylation is a widespread modification that is mediated by site-selective acetyltransferases. KATs (lysine N(epsilon)-acetyltransferases), modify the side chain of specific lysines on histones and other proteins, a central process in regulating gene expression. N(alpha)-terminal acetylation occurs on the ribosome where the alpha amino group of nascent polypeptides is acetylated by NATs (N-terminal acetyltransferase). In yeast, three different NAT complexes were identified NatA, NatB… CONTINUE READING
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