Human N-myc is closely related in organization and nucleotide sequence to c-myc

@article{Kohl1986HumanNI,
  title={Human N-myc is closely related in organization and nucleotide sequence to c-myc},
  author={N. Kohl and E. Legouy and R. DePinho and P. Nisen and Russell K. Smith and C. Gee and F. Alt},
  journal={Nature},
  year={1986},
  volume={319},
  pages={73-77}
}
N-myc, a cellular gene related to the c-myc proto-oncogene1–4, was originally identified on the basis of its very frequent amplification and overexpression in a restricted set of tumours, most notably human neuroblastomas1,2. That N-myc may have a causal role in the genesis of these tumours is suggested by the observation that in the rat embryo fibroblast co-transformation assay5,6 it has a transforming potential similar to that of c-myc7,8. The apparent structural and functional homology of N… Expand
The myc family of nuclear proto-oncogenes.
  • W. Lee
  • Biology, Medicine
  • Cancer treatment and research
  • 1989
Neoplastic transformation by the human gene N-myc.
Isolation and characterization of complementary DNA for N-cym, a gene encoded by the DNA strand opposite to N-myc.
  • B. C. Armstrong, G. Krystal
  • Biology, Medicine
  • Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
  • 1992
myc family oncogenes in the development of normal and neoplastic cells.
Control of c-myc regulation in normal and neoplastic cells.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 55 REFERENCES
N-myc can cooperate with ras to transform normal cells in culture.
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.
Translocations among antibody genes in human cancer.
...
1
2
3
4
5
...