Human Mesothelioma Cells Produce Factors That Stimulate the Production of ltyaluronan by Mesothelial Cells and Fibroblasts

@inproceedings{Asplund2007HumanMC,
  title={Human Mesothelioma Cells Produce Factors That Stimulate the Production of ltyaluronan by Mesothelial Cells and Fibroblasts},
  author={Tomas Asplund and Marjan A. Versnel and Torvard C. Laurent and Paraskevi Heidin},
  year={2007}
}
The hyaluronan production by three human malignant mesothelioma cell lines and nine primary human mesothelial cell types was determined. The mesothelioma cell lines produced only minute amounts of hyaluronan (less than 0.1 pg/106 cells/48 h) whereas mesothelial cells synthesized large quantities of hyaluronan (10-72 ~tg/106 cells/48 h). Conditioned media from the mesothelioma cell lines were investigated for their ability to stimulate hyaluronan production by fibroblasts and mesothelial cells… CONTINUE READING