Human-Induced Pluripotent Stem Cells: In Quest of Clinical Applications

@article{Madonna2012HumanInducedPS,
  title={Human-Induced Pluripotent Stem Cells: In Quest of Clinical Applications},
  author={Rosalinda Madonna},
  journal={Molecular Biotechnology},
  year={2012},
  volume={52},
  pages={193-203}
}
  • R. Madonna
  • Published 3 February 2012
  • Biology
  • Molecular Biotechnology
In the field of regenerative medicine, the development of induced pluripotent stem (iPS) cells may represent a potential strategy to overcome the limitations of human embryonic stem cells (ESCs). iPS cells have the potential to mimic human disease, since they carry the genome of the donor. Hypothetically, with iPS cell technology it is possible to screen patients for a genetic cause of disease (genetic mutation), develop cell lines, reprogram them back to iPS cells, finally differentiate them… 

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