Human IgM molecules that bind staphylococcal protein A contain VHIII H chains.

Abstract

Staphylococcal protein A (SPA) is a bacterial membrane protein which has distinct binding sites for Fc gamma and for the Fab region of some IgM, IgG, IgA, and IgE molecules. This study establishes a structure-function correlation responsible for the binding of Ig Fab regions to SPA. Binding of 24 isolated human monoclonal IgM proteins to SPA was measured in… (More)

Topics

Cite this paper

@article{Sasso1989HumanIM, title={Human IgM molecules that bind staphylococcal protein A contain VHIII H chains.}, author={Emanuele Sasso and Gahl Silverman and Mart Mannik}, journal={Journal of immunology}, year={1989}, volume={142 8}, pages={2778-83} }