Human IgE response to the Schistosoma haematobium 22.6 kDa antigen.

  title={Human IgE response to the Schistosoma haematobium 22.6 kDa antigen.},
  author={Colin M. Fitzsimmons and Tracy J Stewart and Karl F. Hoffmann and Jane L. Grogan and Maria Yazdanbakhsh and David W. Dunne},
  journal={Parasite immunology},
  volume={26 8-9},
In Schistosoma mansoni and S. japonicum infection, the 22.6 kDa tegumental antigens Sm22.6 and Sj22.6 are principal targets for the human IgE response, and levels of IgE to Sm22.6 have been correlated with resistance to re-infection after chemotherapy. S. haematobium is arguably a more important species in terms of human infection, and in this report we describe for the first time the molecular characterization of a cDNA from S. haematobium (Sh22.6) that is closely homologous to Sm22.6 and Sj22… CONTINUE READING

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