Human Ig S gamma regions and their participation in sequential switching to IgE.

Abstract

The Ig isotype switch from IgM to IgE is accompanied by a DNA recombination that joins S mu, the highly repetitive "switch" region upstream of the C mu gene, to the S epsilon region upstream of C epsilon, thereby creating a composite S mu-S epsilon region. In human B cells cultured in vitro with IL-4 to promote the switch to IgE, we previously described… (More)

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Cite this paper

@article{Mills1995HumanIS, title={Human Ig S gamma regions and their participation in sequential switching to IgE.}, author={Frederick C. Mills and Michael P. Mitchell and Nagaradona Harindranath and Edward E. Max}, journal={Journal of immunology}, year={1995}, volume={155 6}, pages={3021-36} }