Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation.

@article{Dentelli1999HumanIS,
  title={Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation.},
  author={Patrizia Dentelli and Lorenzo Del Sorbo and Arturo Rosso and Annarita Molinar and Giovanni Maria Garbarino and Giovanni Camussi and Luigi Pegoraro and Maria Felice Brizzi},
  journal={Journal of immunology},
  year={1999},
  volume={163 4},
  pages={2151-9}
}
Angiogenesis is a critical process for growth of new capillary blood vessels from preexisting capillaries and postcapillary venules, both in physiological and pathological conditions. Endothelial cell proliferation is a major component of angiogenesis and it is regulated by several growth factors. It has been previously shown that the human hemopoietic growth factor IL-3 (hIL-3), predominantly produced by activated T lymphocytes, stimulates both endothelial cell proliferation and functional… CONTINUE READING

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