Human ICE/CED-3 Protease Nomenclature

@article{Alnemri1996HumanIP,
  title={Human ICE/CED-3 Protease Nomenclature},
  author={Emad S. Alnemri and David J. Livingston and Donald W. Nicholson and Guy Salvesen and Nancy A. Thornberry and Winnie Wing-Yin Wong and Junying Yuan},
  journal={Cell},
  year={1996},
  volume={87}
}
It is now clear that members of the ICE/CED-3 protease Philadelphia, Pennsylvania 19107–5541 family play key biological roles in inflammation and e_alnemri@lac.jci.tju.edu mammalian apoptosis. To date, ten homologs of human 2 Vertex Pharmaceuticals, Inc. origin have been published (Figure 1). The frenetic pace Cambridge, Massachusetts 02139 of identification of new homologs has led to inconsistent livingston@vpharm.com and multiple names for many of these enzymes. As a 3 Merck Frosst Centre for… CONTINUE READING
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