Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers.

@article{Maatough2018HumanHP,
  title={Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers.},
  author={Anas Maatough and Grahame Whitfield and Lemlem Brook and D Hsieh and Patricia Palade and Jui-Cheng Hsieh},
  journal={Journal of cellular biochemistry},
  year={2018},
  volume={119 1},
  pages={
          69-80
        }
}
The mammalian hairless protein (HR) is a 130 kDa nuclear transcription factor that is essential for proper skin and hair follicle function. Previous studies have focused on the role of HR in skin maintenance and hair cycling. However, the hairless gene (HR) is also expressed in brain and other tissues, where its role remains poorly understood. HR has been reported to contain functional domains that potentially serve in DNA binding, histone demethylation, nuclear translocation and protein… CONTINUE READING