Human Hair Graying is Naturally Reversible and Linked to Stress

@article{Rosenberg2020HumanHG,
  title={Human Hair Graying is Naturally Reversible and Linked to Stress},
  author={Ayelet Rosenberg and Shannon Rausser and J. Ren and E. Mosharov and Gabriel Sturm and R. T. Ogden and P. Patel and R. Soni and Clay O. Lacefield and R. Paus and M. Picard},
  journal={bioRxiv},
  year={2020}
}
  • Ayelet Rosenberg, Shannon Rausser, +8 authors M. Picard
  • Published 2020
  • Biology
  • bioRxiv
  • Hair graying is a universal hallmark of aging but its mechanisms are insufficiently understood and its reversibility in humans remains uncertain. Moreover, while psychological stress accelerates human biological aging, and triggers hair graying in animals, no prior study has longitudinally examined the stress-to-hair graying connection in humans. Here we develop an approach to quantitatively profile natural graying events and their associated proteomic signatures along individual human hairs… CONTINUE READING

    References

    SHOWING 1-10 OF 115 REFERENCES
    Age-related hair pigment loss.
    • D. Tobin
    • Biology, Medicine
    • Current problems in dermatology
    • 2015
    • 12
    • PDF
    The biology of human hair greying
    • 3
    Senile hair graying: H2O2‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
    • J. M. Wood, H. Decker, +8 authors K. Schallreuter
    • Medicine, Biology
    • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
    • 2009
    • 176
    • PDF
    Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage
    • 166
    Aging of the Hair Follicle Pigmentation System
    • D. Tobin
    • Biology, Medicine
    • International journal of trichology
    • 2009
    • 50
    Graying: gerontobiology of the hair follicle pigmentary unit
    • 259
    The cell biology of human hair follicle pigmentation
    • D. Tobin
    • Biology, Medicine
    • Pigment cell & melanoma research
    • 2011
    • 103