Human Female Genital Tract Infection by the Obligate Intracellular Bacterium Chlamydia trachomatis Elicits Robust Type 2 Immunity

@inproceedings{Miguel2013HumanFG,
  title={Human Female Genital Tract Infection by the Obligate Intracellular
Bacterium Chlamydia trachomatis Elicits Robust Type 2
Immunity},
  author={Rodolfo D Vicetti Miguel and Stephen A. K. Harvey and William A Laframboise and Seth D. Reighard and Dean B. Matthews and Thomas L. Cherpes},
  booktitle={PloS one},
  year={2013}
}
While Chlamydia trachomatis infections are frequently asymptomatic, mechanisms that regulate host response to this intracellular Gram-negative bacterium remain undefined. This investigation thus used peripheral blood mononuclear cells and endometrial tissue from women with or without Chlamydia genital tract infection to better define this response. Initial genome-wide microarray analysis revealed highly elevated expression of matrix metalloproteinase 10 and other molecules characteristic of… CONTINUE READING
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