Human EAG channels are directly modulated by PIP2 as revealed by electrophysiological and optical interference investigations.

@article{Han2016HumanEC,
  title={Human EAG channels are directly modulated by PIP2 as revealed by electrophysiological and optical interference investigations.},
  author={Bo Han and Kunyan He and Chunlin Cai and Yin Tang and Linli Yang and Stefan H. Heinemann and Toshinori Hoshi and Shangwei Hou},
  journal={Scientific reports},
  year={2016},
  volume={6},
  pages={23417}
}
Voltage-gated ether à go-go (EAG) K(+) channels are expressed in various types of cancer cells and also in the central nervous system. Aberrant overactivation of human EAG1 (hEAG1) channels is associated with cancer and neuronal disorders such as Zimmermann-Laband and Temple-Baraitser syndromes. Although hEAG1 channels are recognized as potential… CONTINUE READING