Human Dermal Safety Studies with Eflornithine HCl 13.9% Cream (Vaniqa™), a Novel Treatment for Excessive Facial Hair

  title={Human Dermal Safety Studies with Eflornithine HCl 13.9\% Cream (Vaniqa{\texttrademark}), a Novel Treatment for Excessive Facial Hair},
  author={J. Hickman and F. Huber and M. Palmisano},
  journal={Current Medical Research and Opinion},
  pages={235 - 244}
Summary Eflornithine HCl 13.9% cream (Vaniqa™) is a novel treatment for the management of unwanted facial hair in women. This paper reports the results of four modified open-label, within-subject vehicle-controlled studies evaluating the dermal safety of this topical treatment. In a repeated insult patch test (230 subjects), erythema with oedema occurred in 38.9% of subjects treated with eflornithine HCl 13.9% cream and 4.8% of subjects treated with vehicle cream. Challenge applications at… Expand
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