Human Dedifferentiated Adipocytes Show Similar Properties to Bone Marrow‐Derived Mesenchymal Stem Cells

@article{Poloni2012HumanDA,
  title={Human Dedifferentiated Adipocytes Show Similar Properties to Bone Marrow‐Derived Mesenchymal Stem Cells},
  author={Antonella Poloni and Giulia Maurizi and Pietro Leoni and Federica Serrani and Stefania Mancini and Andrea Frontini and Maria Cristina Zingaretti and Walter Siquini and Riccardo Sarzani and Saverio Cinti},
  journal={STEM CELLS},
  year={2012},
  volume={30}
}
Mature adipocytes are generally considered terminally differentiated because they have lost their proliferative abilities. Here, we studied the gene expression and functional properties of mature adipocytes isolated from human omental and subcutaneous fat tissues. We also focused on dedifferentiated adipocytes in culture and their morphologies and functional changes with respect to mature adipocytes, stromal‐vascular fraction (SVF)‐derived mesenchymal stem cells (MSCs) and bone marrow (BM… 

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