Human DNA Repair Genes
@article{Wood2001HumanDR, title={Human DNA Repair Genes}, author={Richard D. Wood and Michael Mitchell and John G. Sgouros and Tomas Lindahl}, journal={Science}, year={2001}, volume={291}, pages={1284 - 1289} }
Cellular DNA is subjected to continual attack, both by reactive species inside cells and by environmental agents. Toxic and mutagenic consequences are minimized by distinct pathways of repair, and 130 known human DNA repair genes are described here. Notable features presently include four enzymes that can remove uracil from DNA, seven recombination genes related to RAD51, and many recently discovered DNA polymerases that bypass damage, but only one system to remove the main DNA lesions induced…
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