Human Coronavirus NL63, France

@article{Vabret2005HumanCN,
  title={Human Coronavirus NL63, France},
  author={Astrid Vabret and Thomas Mourez and Julia Dina and Lia van der Hoek and Stéphanie Gouarin and Jo{\"e}lle Petitjean and Jacques Brouard and François Freymuth},
  journal={Emerging Infectious Diseases},
  year={2005},
  volume={11},
  pages={1225 - 1229}
}
Coronavirus NL63 was found in hospitalized children with upper and lower respiratory infections. 

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References

SHOWING 1-10 OF 31 REFERENCES
Coronavirus 229E-Related Pneumonia in Immunocompromised Patients
  • F. PèneA. Merlat P. Lebon
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2003
TLDR
On the basis of this report, coronaviruses should be considered as potential causative microorganisms of pneumonia in immunocompromised patients.
Association of coronavirus infection with neonatal necrotizing enterocolitis.
TLDR
In many aspects the human disease is reminiscent of experimental necrotizing enterocolitis obtained by infection of germ-free newborn animals, as reported in the literature.
A newly discovered human pneumovirus isolated from young children with respiratory tract disease
TLDR
Serological studies showed that by the age of five years, virtually all children in the Netherlands have been exposed to human metapneumovirus and that the virus has been circulating in humans for at least 50 years.
An Outbreak of Coronavirus OC43 Respiratory Infection in Normandy, France
TLDR
This study shows that an outbreak of HCoV OC43 respiratory infection was responsible for the lower respiratory tract symptoms observed in nearly one-third of patients identified by active surveillance for coronavirus infection.
Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China
TLDR
The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
VIROLOGIC STUDIES OF ACUTE RESPIRATORY DISEASE IN YOUNG ADULTS
TLDR
In a surveillance study of acute respiratory disease in medical students, infection with coronavirus 229E was identified by virus isolation and serologic studies and the frequency of significant rise in neutralizing antibody titer with reinfection was inversely related to pre-infection levels of this antibody.
Identification of a new human coronavirus
TLDR
Screening of clinical specimens from individuals suffering from respiratory illness identified seven additional HCoV-NL63-infected individuals, indicating that the virus was widely spread within the human population.
SEROEPIDEMIOLOGIC STUDIES OF CORONAVIRUS INFECTION IN ADULTS AND CHILDREN1
TLDR
In adults with upper respiratory disease, two “outbreaks” of coronavirus infection occurred, one during the winter of 1965–1966 associated with complement fixing (CF) antibody responses to OC38, OC43 and MHV, and the other during the following winter associated with CF antibodies to 229E.
A previously undescribed coronavirus associated with respiratory disease in humans.
TLDR
The identification and characterization of a not previously recognized coronavirus obtained from an 8-mo-old boy suffering from pneumonia is described, revealing that it is most closely related to porcine epidemic diarrhea virus and HCoV 229E.
...
...