Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations

@inproceedings{Melsen2016HumanCA,
  title={Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations},
  author={Janine E Melsen and Gertjan Lugthart and Arjan C Lankester and Marco W Schilham},
  booktitle={Front. Immunol.},
  year={2016}
}
Two human natural killer (NK) cell subsets are usually distinguished, displaying the CD56(dim)CD16(+) and the CD56(bright)CD16(-/+) phenotype. This distinction is based on NK cells present in blood, where the CD56(dim) NK cells predominate. However, CD56(bright) NK cells outnumber CD56(dim) NK cells in the human body due to the fact that they are predominant in peripheral and lymphoid tissues. Interestingly, within the total CD56(bright) NK cell compartment, a major phenotypical and functional… CONTINUE READING
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CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver

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