Human Cancer Biology MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer

Abstract

Purpose:Theprocess ofmetastases involves the dissociation of cells from theprimary tumor, penetration into the basement membrane, invasion, and exiting from the vasculature to seed and colonize distant tissues. miR-200a is involved in this multistep metastatic cascade. This study aimed to test the hypothesis that miR-200a promotes metastasis through… (More)

Topics

5 Figures and Tables