Human CD4 T cell epitopes selective for Vaccinia versus Variola virus.


Due to the high degree of sequence identity between Orthopoxvirus species, the specific B and T cell responses raised against these viruses are largely cross-reactive and poorly selective. We therefore searched for CD4 T cell epitopes present in the conserved parts of the Vaccinia genome (VACV) but absent from Variola viruses (VARV), with a view to… (More)
DOI: 10.1016/j.molimm.2012.10.011


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