Human CD4+CD25+ regulatory T cells.

  title={Human CD4+CD25+ regulatory T cells.},
  author={Clare Baecher-Allan and Vissia Viglietta and David A. Hafler},
  journal={Seminars in immunology},
  volume={16 2},
In this report, we review studies of human CD4+CD25+ regulatory T cells (T-reg). Although lagging a few years behind the discovery of these cells in the mouse, the equivalent population of CD4+CD25+ regulatory T cells has also been isolated from human peripheral blood, thymus, lymph nodes and cord blood. In general, the characteristics of this T cell subset are strikingly similar between mouse and man. In the recent explosion of research reports on human CD4+CD25+ cells, although the majority… CONTINUE READING
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