Human CD34+AC133+VEGFR-2+ cells are not endothelial progenitor cells but distinct, primitive hematopoietic progenitors.

@article{Case2007HumanCC,
  title={Human CD34+AC133+VEGFR-2+ cells are not endothelial progenitor cells but distinct, primitive hematopoietic progenitors.},
  author={J. Case and L. Mead and Waylan K. Bessler and D. Prater and H. White and M. Saadatzadeh and J. Bhavsar and M. Yoder and L. Haneline and D. Ingram},
  journal={Experimental hematology},
  year={2007},
  volume={35 7},
  pages={
          1109-18
        }
}
OBJECTIVE Endothelial progenitor cells (EPCs) are used for angiogenic therapies or as biomarkers to assess cardiovascular disease risk. However, there is no uniform definition of an EPC, which confounds EPC studies. EPCs are widely described as cells that coexpress the cell-surface antigens CD34, AC133, and vascular endothelial growth factor receptor-2 (VEGFR-2). These antigens are also expressed on primitive hematopoietic progenitor cells (HPCs). Remarkably, despite their original… Expand
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